Development Pipeline
At Biora, we are creating innovative smart-pill technologies to improve patients’ lives. Our ingestible drug-device combinations could enable new treatment approaches in the delivery of oral biotherapeutics. We are focused on two primary areas:
Targeted Therapeutics Pipeline
Our Targeted Therapeutics program uses an ingestible smart capsule designed for targeted delivery of therapeutics in the gastrointestinal tract to improve the treatment of IBD. Delivering therapeutics directly to the site of disease could enable safer and more effective drug therapies.
| Program | Indication | Design / Feasibility | Preclinical | Clinical |
|---|---|---|---|---|
DDS |
— | |||
PGN-600 |
Ulcerative Colitis | |||
PGN-001 |
Ulcerative Colitis | |||
Systemic Therapeutics Pipeline
Our Systemic Therapeutics program uses an ingestible capsule designed for needle-free delivery of biotherapeutics into intestinal tissue for enhanced systemic uptake. With more frequent administration, oral delivery has the potential to improve drug efficacy and safety versus current injection regimens.
| Program | Indication | Design / Feasibility | Preclinical | Clinical |
|---|---|---|---|---|
OBDS |
— | |||
PGN-OB2 |
Diabetes | |||
PGN-OB1 |
Autoimmune | |||
Ionis Collaboration |
Undisclosed | |||
Large Pharma 1 Collaboration |
Undisclosed | |||
Large Pharma 2 Collaboration |
Undisclosed | |||
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